Microsoft has spotted a malvertising campaign that downloaded nastyware hosted on GitHub and exposed nearly a million devices to information thieves. From a report: Discovered by Microsoft Threat Intelligence late last year, the campaign saw pirate vid-streaming websites embed malvertising redirectors to generate pay-per-view or pay-per-click revenue from malvertising platforms. "These redirectors subsequently routed traffic through one or two additional malicious redirectors, ultimately leading to another website, such as a malware or tech support scam website, which then redirected to GitHub" according to Microsoft's threat research team. GitHub hosted a first-stage payload that installed code that dropped two other payloads. One gathered system configuration info such as data on memory size, graphics capabilities, screen resolution, the operating system present, and user paths. Third-stage payloads varied but most "conducted additional malicious activities such as command and control (C2) to download additional files and to exfiltrate data, as well as defense evasion techniques."

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AmiMoJo writes: In September 2023, KrebsOnSecurity published findings from security researchers who concluded that a series of six-figure cyberheists across dozens of victims resulted from thieves cracking master passwords stolen from the password manager service LastPass in 2022. In a court filing last week, U.S. federal agents investigating a spectacular $150 million cryptocurrency heist said they had reached the same conclusion. On March 6, federal prosecutors in northern California said they seized approximately $24 million worth of cryptocurrencies that were clawed back following a $150 million cyberheist on Jan. 30, 2024. The complaint refers to the person robbed only as 'Victim-1,' but according to blockchain security researcher ZachXBT the theft was perpetrated against Chris Larsen, the co-founder of the cryptocurrency platform Ripple. ZachXBT was the first to report on the heist, of which approximately $24 million was frozen by the feds before it could be withdrawn. This week's action by the government merely allows investigators to officially seize the frozen funds. But there is an important conclusion in this seizure document: It basically says the U.S. Secret Service and the FBI agree with the findings of the LastPass breach story published here in September 2023.

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smooth wombat writes: In what can only be described as a no-brainer, Volkswagen has announced it will have once again have physical buttons in all its vehicles. As Andreas Mindt, design chief at the company said, removing buttons was "a mistake". "From the ID 2all onwards, we will have physical buttons for the five most important functions -- the volume, the heating on each side of the car, the fans and the hazard light -- below the screen," he explained, adding: "It's not a phone: it's a car." This doesn't mean touch screens are set to disappear on new Volkswagens, just that drivers will now have the option of physical controls for their most used day-to-day tasks. The new controls are set to make their debut in the ID.2all, a small, budget EV set to debut in Europe.

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Nearly one in four U.S. tech jobs posted in 2025 require AI skills, according to data from the University of Maryland's AI job tracker, as companies across sectors adapt to the technology. Companies across healthcare, retail and utilities are increasingly seeking candidates who can integrate AI into existing roles rather than creating entirely new positions, with these skills commanding premium pay and greater job security. The information sector leads with 36% of IT jobs in January seeking AI expertise, followed by finance and professional services firms. AI-related listings account for 1.3% of all job postings nationwide. New AI job postings surged 68% since ChatGPT's launch in late 2022 through end-2024, while tech postings overall fell 27% during the same period.

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An anonymous reader shares a report: AI excels at following instructions -- but it's not pushing the boundaries of knowledge, says Thomas Wolf. The chief science officer and cofounder of Hugging Face, an open-source AI company backed by Amazon and Nvidia, analyzed the limits of large language models. He wrote that the field produces "overly compliant helpers" rather than revolutionaries. Right now, AI isn't creating new knowledge, Wolf wrote. Instead, it's just filling in the blanks between existing facts -- what he called "manifold filling." Wolf argues that for AI to drive real scientific breakthroughs, it needs to do more than retrieve and synthesize information. AI should question its own training data, take counterintuitive approaches, generate new ideas from minimal input, and ask unexpected questions that open new research paths. Wolf also weighed in on the idea of a "compressed 21st century" -- a concept from an October essay by Anthropic's CEO Dario Amodei, "Machine of Loving Grace." Amodei wrote that AI could accelerate scientific progress so much that discoveries expected over the next 100 years could happen in just five to 10. "I read this essay twice. The first time I was totally amazed: AI will change everything in science in five years, I thought!" Wolf wrote on X. "Re-reading it, I realized that much of it seemed like wishful thinking at best." Unless AI research shifts gears, Wolf warned, we won't get a new Albert Einstein in a data center -- just a future filled with "yes-men on servers."

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August, 2023: Thousands of Crypto Scammers are Enslaved by Human-Trafficking Gangsters, Says Bloomberg Reporter. ("They'd lure young people from across Southeast Asia...with the promise of well-paying jobs in customer service or online gambling.") February, 2025: A coordinated response begins by Thai, Chinese and Myanmar authorities, which includes cutting power, internet, and fuel supplies to the scam centers. Today: The Associated Press reports that thousands of the people liberated from locked compounds in Myanmar now "have found themselves trapped once again, this time in overcrowded facilities with no medical care, limited food and no idea when they'll be sent home." Thousands of sick, exhausted and terrified young men and women, from countries all over the world squat in rows, packed shoulder to shoulder, surgical masks covering their mouths and eyes. Their nightmare was supposed to be over... The armed groups who are holding the survivors, as well as Thai officials across the border, say they are awaiting action from the detainees' home governments. It's one of the largest potential rescues of forced laborers in modern history, but advocates say the first major effort to crack down on the cyber scam industry has turned into a growing humanitarian crisis... An unconfirmed list provided by authorities in Myanmar says they're holding citizens from 29 countries including Philippines, Kenya and the Czech Republic. Authorities in Thailand say they cannot allow foreigners to cross the border from Myanmar unless they can be sent home immediately, leaving many to wait for help from embassies that has been long in coming. China sent a chartered flight Thursday to the tiny Mae Sot airport to pick up a group of its citizens, but few other governments have matched that. There are roughly 130 Ethiopians waiting in a Thai military base, stuck for want of a $600 plane ticket. Dozens of Indonesians were bused out one morning last week, pushing suitcases and carrying plastic bags with their meager possessions as they headed to Bangkok for a flight home... The recent abrupt halt to U.S. foreign aid funding has made it even harder to get help to released scam center workers... It's not clear how much of an effect these releases will have on the criminal groups that run the scam centers. February marked the third time the Thais have cut internet or electricity to towns across the river. Each time, the compounds have managed to work around the cuts. Large compounds have access to diesel-powered generators, as well as access to internet provider Starlink, experts working with law enforcement say. The article also points out that "The people released are just a small fraction of what could be 300,000 people working in similar scam operations across the region, according to an estimate from the United States Institute of Peace. Human rights groups and analysts add that the networks that run these illegal scams will continue to operate unless much broader action is taken against them..." "The United Nations Office on Drugs and Crimes estimates that between $18 billion and $37 billion was lost in Asia alone in 2023, with minimal government action against the criminal industry's spread."

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The Washington Post reports: Meta was willing to go to extreme lengths to censor content and shut down political dissent in a failed attempt to win the approval of the Chinese Communist Party and bring Facebook to millions of internet users in China, according to a new whistleblower complaint from a former global policy director at the company. The complaint by Sarah Wynn-Williams, who worked on a team handling China policy, alleges that the social media giant so desperately wanted to enter the lucrative China market that it was willing to allow the ruling party to oversee all social media content appearing in the country and quash dissenting opinions. Meta, then called Facebook, developed a censorship system for China in 2015 and planned to install a "chief editor" who would decide what content to remove and could shut down the entire site during times of "social unrest," according to a copy of the 78-page complaint exclusively seen by The Washington Post. Meta chief executive Mark Zuckerberg also agreed to crack down on the account of a high-profile Chinese dissident living in the United States following pressure from a high-ranking Chinese official the company hoped would help them enter China, according to the complaint, which was filed in April to the Securities and Exchange Commission [SEC]. When asked about its efforts to enter China, Meta executives repeatedly "stonewalled and provided nonresponsive or misleading information" to investors and American regulators, according to the complaint. Wynn-Williams bolstered her SEC complaint with internal Meta documents about the company's plans, which were reviewed by The Post. Wynn-Williams, who was fired from her job in 2017, is also scheduled to release a memoir this week documenting her time at the company, titled "Careless People: A Cautionary Tale of Power, Greed, and Lost Idealism." According to a memo in the complaint, Meta leaders faced aggressive pressure by Chinese government officials to host Chinese users' data to local data centers, which Wynn-Williams alleges would have made it easier for the Chinese Communist Party to covertly obtain the personal information of its citizens. Wynn-Williams told the Washington Post that "for many years Meta has been working hand in glove with the Chinese Communist Party, briefing them on the latest technological developments and lying about it." Reached for a comment, Meta spokesman Andy Stone told the Washington Post it was "no secret" they'd been interested in operating in China. "This was widely reported beginning a decade ago. We ultimately opted not to go through with the ideas we'd explored, which Mark Zuckerberg announced in 2019." Although the Post shares new details about what a Facebook privacy policy staffer offer China in negotations in 2014. ("In exchange for the ability to establish operations in China, FB will agree to grant the Chinese government access to Chinese users' data — including Hongkongese users' data.") The Post also describes one iteration of a proposed agreement in 2015. "To aid the effort, Meta built a censorship system specially designed for China to review, including the ability to automatically detect restricted terms and popular content on Facebook, according to the complaint... "In 2017, Meta covertly launched a handful of social apps under the name of a China-based company created by one of its employees, according to the complaint."

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As oft stated, the "right" way to validate emails is to do a bare minimum sanity check on format, and then send a verification message to the email address the user supplied; it's the only way to ensure that what they gave you isn't just syntactically valid, but is actually usable.

But even that simple approach leaves places to go wrong. Take a look at this code, from Lana.

public function getEmailValidationErrors($data): array { $errors = []; if (isset($data["email"]) && !empty($data["email"])) { if (!str_contains($data["email"], "@")) { $error["email"] = "FORM.CONTACT_DETAILS.ERRORS.NO_AT"; } if (!str_contains($data["email"], ".")) { $error["email"] = "FORM.CONTACT_DETAILS.ERRORS.NO_DOT"; } if (strrpos($data["email"], "@") > strrpos($data["email"], ".")) { $error["email"] = "FORM.CONTACT_DETAILS.ERRORS.NO_TLD"; } } if (isset($data["email1"]) && !empty($data["email1"])) { if (!str_contains($data["email1"], "@")) { $error["email1"] = "FORM.CONTACT_DETAILS.ERRORS.NO_AT"; } if (!str_contains($data["email1"], ".")) { $error["email1"] = "FORM.CONTACT_DETAILS.ERRORS.NO_DOT"; } if (strrpos($data["email1"], "@") > strrpos($data["email1"], ".")) { $error["email1"] = "FORM.CONTACT_DETAILS.ERRORS.NO_TLD"; } } if (isset($data["email2"]) && !empty($data["email2"])) { if (!str_contains($data["email2"], "@")) { $error["email2"] = "FORM.CONTACT_DETAILS.ERRORS.NO_AT"; } if (!str_contains($data["email2"], ".")) { $error["email2"] = "FORM.CONTACT_DETAILS.ERRORS.NO_DOT"; } if (strrpos($data["email2"], "@") > strrpos($data["email2"], ".")) { $error["email2"] = "FORM.CONTACT_DETAILS.ERRORS.NO_TLD"; } } if (isset($data["email3"]) && !empty($data["email3"])) { if (!str_contains($data["email3"], "@")) { $error["email3"] = "FORM.CONTACT_DETAILS.ERRORS.NO_AT"; } if (!str_contains($data["email3"], ".")) { $error["email3"] = "FORM.CONTACT_DETAILS.ERRORS.NO_DOT"; } if (strrpos($data["email3"], "@") > strrpos($data["email3"], ".")) { $error["email3"] = "FORM.CONTACT_DETAILS.ERRORS.NO_TLD"; } } return $errors; }

Let's start with the obvious problem: repetition. This function doesn't validate simply one email, but four, by copy/pasting the same logic multiple times. Lana didn't supply the repeated blocks, just noted that they existed, so let's not pick on the bad names: "email1", etc.- that's just my placeholder. I assume it's different contact types for a customer, or similar.

Now, the other problems range from trivial to comical. First, the PHP function empty returns true if the variable has a zero/falsy value or is not set, which means it implies an isset, making the first branch redundant. That's trivial.

The way the checks get logged into the $error array, they can overwrite each other, meaning if you forget the "@" and the ".", it'll only complain about the ".", but if you forget the ".", it'll complain about not having a valid TLD (the "NO_DOT" error will never be output). That's silly.

Finally, the $errors array is the return value, but the $error array is where we store our errors, meaning this function doesn't return anything in the first place. And that means that it's a email validation function which doesn't do anything at all, which honestly- probably for the best.

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Nominated for 10 Oscars, The Brutalist (directed and produced by Brady Corbet) has an "intriguing and controversial technical feature," according to the Baffler, that threatens to turn movie-viewing into "a drab appreciation of machine-managed flawlessness, and acting less interesting..." In January, the film's editor Dávid Jancsó revealed that he and Corbet used tools from AI speech software company Respeecher to make the Hungarian-language dialogue spoken by Adrien Brody (who plays the protagonist, Hungarian émigré architect László Tóth) and Felicity Jones (who plays Tóth's wife Erzsébet) sound more Hungarian. In response to the ensuing backlash, Corbet clarified that the actors worked "for months" with a dialect coach to perfect their accents; AI was used "in Hungarian language dialogue editing only, specifically to refine certain vowels and letters for accuracy...." Defenders of this slimy deception claim the use of AI in film is no different than CGI or automated dialogue replacement, tools commonly deployed in the editing suite for picture and audio enhancement. But CGI and ADR don't tamper with the substance of a performance, which is what's at issue here.... AI seems poised to decimate the voice acting industry; how long will it be before filmmakers give up on the whole time-wasting business of dialect coaching and language research and toss their performers' untrained vocalizations directly into the linguistic Instant Pot...? "Adrien and Felicity's performances are completely their own," Corbet has argued. Only, they're not. Brody and Jones's performances may now be authentic to spoken Hungarian, but they're no longer authentic to themselves: at least in the parts of the film with Hungarian dialogue, the acting stands more as a monument to the prowess of the voice-matching software than that of the actors... AI is a different beast from color film, or the Louma crane, or the hand-held camera: it's steroidal, aesthetically corrupting, and unlike these earlier advances it confronts the filmmaker with real ethical questions... Use implies complicity. To incorporate AI into the production of art today, no matter how sparingly or subtly, is to endorse Silicon Valley's politics and worldview: its exploitation of both producers and "users," its blithe indifference to the social impact of post-automation layoffs and the environmental assault of industrial data processing, its cramped and uninteresting idea of imagination, its petrification of creation. It's a vote for the assholes... In short, the essays calls this "recourse to corrective AI" a "filmmaking prosthesis that cheats the viewer and cheapens the performances." And ironically this clashes with the film's depiction of a "principled artist," according to the article. ("Some of the 'retro' digital renderings in the memorial video included in this scene were also, Corbet has admitted, produced with the help of AI.") The essay notes that several of 2024's other Oscar-nominated films also employed Respeecher, including Dune: Part Two and Emilia Pérez. "What matters here is not this particular infraction but the precedent it sets, the course it establishes for culture."

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Red Hat product manager Pau Garcia Quiles (also long-time Slashdot reader paugq) spotted an interesting project on GitHub: Free95, a new lean, Windows-compatible operating system is available from GitHub. In its current form, it can run very basic Win32 GUI and console applications, but its developer promises to keep working on it to reach DirectX and even game compatibility. "Free95 is your friendly Windows Environment with an added trust of the open source community," according to its README file. (It's licensed under the GPL-3.0 license.) And in answer to the question "Why?" it responds "To remove Windows's bloat, and security problems. Being controlled by a large corporation is unsettling." "It's still in-development of course," the developer post recently on Reddit, "and I'll appreciate anyone who'd like to contribute." In one comment they claim Free95 is "much more lightweight, simpler and faster than ReactOS." And looking to the future, they add "I might do DirectX stuff and make some games run. Or, what about DOOM?"

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Adafruit Industries used large language model (LLM) tool Claude Code to streamline hardware development, writes managing director ptorrone. In a demo video Limor 'Ladyada' Fried compares the LLM's command-line interface to working with the build-automation tool CMake or "a weird cross between IRC and a BBS." The first step was converting a PDF of the hardware's datasheet into text, and Claude Code first displays the appropriate Bash command, while asking "Do you want to proceed?" ("What's nice is that it doesn't make changes, even though it has write access to files in the directory...") Eventually from the data sheet it creates things like an accurate register map, C++ headers, and even license text — and more. "We are using it to automate parts of the coding and debugging process for an Arduino-compatible Metro Mini board with an OPT 4048 color sensor," writes ptorrone: Using Claude Code's shell access, we can compile, upload, and test code in a semi-automated workflow, allowing the LLM to suggest fixes for errors along the way... While the AI isn't perfect for high-level driver development, it's proving VERY useful for tedious debugging and super-fast iterative improvements, bringing hardware automation closer to ...reality. In the video Fried describes it like this. "I have a full debugging cycle, where I'm there — I'm like driving the car — but I have this copilot that's telling me where to go..." "I feel like I'm getting closer to having a semi-automated way of doing driver development."

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NPR reports on "a monster black hole that's been lurking unseen in the galaxy next door." This appears to be the closest supermassive black hole outside our Milky Way galaxy, according to a report that's appearing in The Astrophysical Journal... "Now that there is strong evidence that it should be there, you can rest assured that we are very excitedly following up," says Jesse Han of the Center for Astrophysics, Harvard & Smithsonian, who led the study... Han and his colleagues realized that this black hole must exist when they were studying so-called hypervelocity stars... [T]hey started out as normal stars that were part of a binary system, or two stars orbiting each other. When that kind of pair ventures too close to a supermassive black hole, says Han, "what can happen is one of the stars can get captured by the black hole. It is basically ripped apart from its companion." The bereft companion star, meanwhile, gets flung away, going at ridiculously high speeds. It's as if the black hole basically hurled it out of the galaxy. And that explains some of what's happening in our own galaxy, writes Space.com: Tracing the trajectory of these super-speed stars using the European Space Agency's star-tracking Gaia satellite, the researchers discovered that around half of them were accelerated by the Milky Way's own supermassive black hole, Sagittarius A*. The other half, the team believes, likely fled to the outskirts of the Milky Way after a gravitational encounter with a supermassive black hole at the heart of the LMC separated these stars from their stellar binary partners. "It is astounding to realize that we have another supermassive black hole just down the block, cosmically speaking," team leader Jesse Han of the Center for Astrophysics | Harvard & Smithsonian (CfA) said in a statement. "Black holes are so stealthy that this one has been practically under our noses this whole time." "Their calculations suggest that the Large Magellanic Cloud must be harboring a black hole that's about 600,000 times the mass of our Sun," adds NPR. "That's smaller than the black hole at the center of the Milky Way, which is about 4 million times more massive than the Sun." Astronomers had previously thought the Large Magellanic Cloud should have a big black hole, but until now there's been no evidence of it, says Han... Now, though, astronomers have a better sense of where to hunt for any X-ray, radio, or visible-light signatures that are the telltale signs of an invisible black hole that's devouring everything nearby. "It is within the realm of possibilities that it is already detectable in radio and X-ray and optical," says Han. "We just haven't looked at the right place."

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gdm (Slashdot reader #97,336) writes: A study published in Transportation Research Interdisciplinary Perspectives investigates how ants avoid traffic jams.... Quoting the abstract: "The results show that ants adopt specific traffic strategies (platoon formation, quasi-constant speed and no overtaking maneuvers) that help avoid jam phenomena, even at high density." "Researchers are now studying these insects' cooperative tactics to learn how to program self-driving cars that don't jam up," writes Scientific American: "We're maximizing the interests of individuals, [which] is why, at a given point, you start to have a traffic jam," says study co-author Nicola Pugno, who studies sustainable engineering at the University of Trento in Italy. But self-driving cars, if they one day become ubiquitous, could have more cooperative programming. In one vision of this future, autonomous vehicles would share information with nearby cars to optimize traffic flow — perhaps, the researchers suggest, by prioritizing constant speeds and headways or by not passing others on the road... Today's drivers can learn at least one thing from ants to avoid causing a traffic jam, says Katsuhiro Nishinari [a mathematical physicist at the University of Tokyo, who studies traffic]: don't tailgate. By leaving room between their car and the one ahead of them, drivers can absorb a wave of braking in dense traffic conditions that would otherwise be amplified into a full-blown "phantom" traffic jam with no obvious cause. "Just keeping away," he says, can help traffic flow smoothly. In the article the researchers admit there are differences between humans stuck in traffic and ants. "Unlike cars, ants don't crash; they can literally walk over one another." And if they're backed up in a tunnel, "they'll find a way to walk on the ceiling!"

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Philosophy/ethics professor Troy Jollimore looks at the implications of a world where many students are submitting AI-generated essays. ("Sometimes they will provide quotations, giving page numbers that, as often as not, do not seem to correspond to anything in the actual world...") Ideally if the students write the essays themselves, "some of them start to feel it. They begin to grasp that thinking well, and in an informed manner, really is different from thinking poorly and from a position of ignorance. That moment, when you start to understand the power of clear thinking, is crucial. "The trouble with generative AI is that it short-circuits that process entirely." One begins to suspect that a great many students wanted this all along: to make it through college unaltered, unscathed. To be precisely the same person at graduation, and after, as they were on the first day they arrived on campus. As if the whole experience had never really happened at all. I once believed my students and I were in this together, engaged in a shared intellectual pursuit. That faith has been obliterated over the past few semesters. It's not just the sheer volume of assignments that appear to be entirely generated by AI — papers that show no sign the student has listened to a lecture, done any of the assigned reading, or even briefly entertained a single concept from the course... It's other things too... The students who beg you to reconsider the zero you gave them in order not to lose their scholarship. (I want to say to them: Shouldn't that scholarship be going to ChatGPT?â) It's also, and especially, the students who look at you mystified. The use of AI already seems so natural to so many of them, so much an inevitability and an accepted feature of the educational landscape, that any prohibition strikes them as nonsensical. Don't we instructors understand that today's students will be able, will indeed be expected, to use AI when they enter the workforce? Writing is no longer something people will have to do in order to get a job. Or so, at any rate, a number of them have told me. Which is why, they argue, forcing them to write in college makes no sense. That mystified look does not vanish — indeed, it sometimes intensifies — when I respond by saying: Look, even if that were true, you have to understand that I don't equate education with job training. What do you mean? they might then ask. And I say: I'm not really concerned with your future job. I want to prepare you for life... My students have been shaped by a culture that has long doubted the value of being able to think and write for oneself — and that is increasingly convinced of the power of a machine to do both for us. As a result, when it comes to writing their own papers, they simply disregard it. They look at instructors who levy such prohibitions as irritating anachronisms, relics of a bygone, pre-ChatGPT age.... As I go on, I find that more of the time, energy, and resources I have for teaching are dedicated to dealing with this issue. I am doing less and less actual teaching, more and more policing. Sometimes I try to remember the last time I actually looked forward to walking into a classroom. It's been a while.

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Slashdot covered the Bulwer-Lytton Fiction Contest in 2008 and 2010 — though it's been running since 1983. Entrants competed to write the worst-possible first sentence for a novel, in a contest started by English professor Scott E. Rice at San Jose State University (which sponsored the contest). In its first year it drew over 10,000 entries! Over the years the bad first sentences were even collected into actual books (that were edited by Rice). But after 43 years, Rice delivered his own disappointing first sentence. "It is with deep regrets that I announce the conclusion of the Bulwer-Lytton Fiction Contest." Being a year and a half older than Joseph Biden, I find the BLFC becoming increasingly burdensome and would like to put myself out to pasture while I still have some vim and vigor! When I initiated the competition in 1983, inviting entrants to submit bad opening sentences to imaginary novels, I never dreamed that we would receive thousands of entrants from all over the U.S. and the globe, or that the contest would survive for over four decades. I am especially grateful to our entrants for keeping the contest alive and to our Panel of Undistinguished Judges who dutifully selected each year's "winners." And, of course, I would like to thank my daughter, EJ, who has been indispensable the last several years of the contest. It's been 42 good years but, alas, all good things must come to an end. Rest assured we're keeping the BLFC spirit alive by maintaining our archive for posterity so that generations and generations hence may witness your greatness! His daughter EJ added their own words of thanks: Lastly, any little bit you could spare towards helping us keep the archive going (a few bucks is great!) would be greatly appreciated (EJ's Venmo is @elizabeth-rice-12). Thank you so much for your joy and enthusiasm — the noble Bulweriers have made working on the contest a treasure!!

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Damaged corneas were repaired at a Harvard teaching hospital in a unique clinical trial, reports New Atlas: Since it's on the frontline of potential hazards from the outside world, the cornea features a population of limbal epithelial stem cells, which repair minor damage to keep the surface smooth and functional... The new study, conducted by scientists at Massachusetts Eye and Ear, investigated a new treatment called cultivated autologous limbal epithelial cells (CALEC). This involves removing stem cells from a patient's uninjured eye, growing their population in the lab for a few weeks, then surgically transplanting them into the injured eye. The phase 1/2 trial recruited 14 patients to undergo the procedure, and followed them for 18 months afterwards... By the first checkup at three months, the corneas of seven (50%) of the participants had been completely restored. By the 12-month mark, that number had increased to 11 (79%) patients. Two other participants met the definition for partial success, so the team claims an overall success rate of 92% for CALEC.

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Slashdot reader databasecowgirl writes: The Times is reporting an interesting study published in Science in which mice demonstrated doing first aid. In the replicated study, an anaesthetised mouse is exposed to another mouse who recognises the distress and clears airway to revive the unconscious mouse. The mice had never seen an unconscious animal before, so the behaviour is thought to be instinctive. From the Times: Large social mammals have previously been documented lending assistance to each other. Chimpanzees have been seen tending to wounded companions, dolphins are known to push distressed pod members to the surface to help them breathe, and elephants have been observed assisting their ailing relatives. Never before, however, has such a meticulous, paws-on approach to first aid been recorded in a creature as small as a mouse.

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"McDonald's is giving its 43,000 restaurants a technology makeover," reports the Wall Street Journal, including AI-enabled drive-throughs and AI-powered tools for managers — as well as internet-connected kitchen equipment. "Technology solutions will alleviate the stress...." says McDonald's CIO Brian Rice. McDonald's tapped Google Cloud in late 2023 to bring more computing power to each of its restaurants — giving them the ability to process and analyze data on-site... a faster, cheaper option than sending data to the cloud, especially in more far-flung locations with less reliable cloud connections, said Rice... Edge computing will enable applications like predicting when kitchen equipment — such as fryers and its notorious McFlurry ice cream machines — is likely to break down, Rice said. The burger chain said its suppliers have begun installing sensors on kitchen equipment that will feed data to the edge computing system and give franchisees a "real-time" view into how their restaurants are operating. AI can then analyze that data for early signs of a maintenance problem. McDonald's is also exploring the use of computer vision, the form of AI behind facial recognition, in store-mounted cameras to determine whether orders are accurate before they're handed to customers, he said. "If we can proactively address those issues before they occur, that's going to mean smoother operations in the future," Rice added... Additionally, the ability to tap edge computing will power voice AI at the drive-through, a capability McDonald's is also working with Google's cloud-computing arm to explore, Rice said. The company has been experimenting with voice-activated drive-throughs and robotic deep fryers since 2019, and ended its partnership with International Business Machines to test automated order-taking at the drive-through in 2024. Edge computing will also help McDonald's restaurant managers oversee their in-store operations. The burger giant is looking to create a "generative AI virtual manager," Rice said, which handles administrative tasks such as shift scheduling on managers' behalf. Fast-food giant Yum Brands' Pizza Hut and Taco Bell have explored similar capabilities.

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A blog post from the Stanford University School of Medicine attempts to answer the question: What's the deal with the gut-brain connection? It affects your mood, your sleep, even your motivation to exercise. There's convincing evidence that it's the starting point for Parkinson's disease and could be responsible for long COVID's cognitive effects. And it sits about 2 feet below your brain. The gut plays an obvious role in our health by digesting what we eat and extracting nutrients. But there's a growing appreciation among scientists that our digestive systems affect our general well-being in a much broader fashion. One fascinating aspect of the gut's widespread impact on health is its direct influence on and communication with the brain, a conduit known as the gut-brain axis. Through direct signals from the vagus nerve, [which] connects the brain and the gut, as well as through molecules secreted into the bloodstream from our gut microbes and immune cells that traffic from the gut to the rest of the body, our brains and our digestive tracts are in constant communication. And when that communication goes off the rails, diseases and disorders can result. The gut-brain connection is a key part of how the brain forms a picture of the rest of the body, a phenomenon known as interoception, explained Christoph Thaiss, PhD, an assistant professor of pathology at Stanford Medicine... The gut also contains the largest number of neurons outside the brain of any structure in the body — more than 100 million neurons line the human digestive tract, from the esophagus to the anus. These cells make up what is known as the enteric nervous system, which some scientists refer to as a "second brain." The enteric nervous system is more brain-like than other peripheral nerves because it consists of lots of different types of neurons that communicate with each other, while other peripheral nerves primarily serve to communicate between the brain and the body, said Julia Kaltschmidt, PhD, the Firmenich Next Generation Faculty Scholar and an associate professor of neurosurgery. In fact, the gut's nervous system can act alone. Scientists have found that if they remove an animal's gut and bathe it in a special fluid designed to keep neurons alive, the gut continues to contract, pushing its contents from top to bottom.

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Last week Google urged the U.S. government not to break up the company — but apparently, it didn't work. In a new filing Friday, America's Justice Department "reiterated its November proposal that Google be forced to sell its Chrome web browser," reports the Washington Post, "to address a federal judge finding the company guilty of being an illegal monopoly in August." The government also kept a proposal that Google be banned from paying other companies to give its search engine preferential placement on their apps and phones. At the same time, the government dropped its demand that Google sell its stakes in AI start-ups after one of the start-ups, Anthropic AI, argued that it needed Google's money to compete in the fast-growing industry. The government's final proposal "reaffirms that Google must divest the Chrome browser — an important search access point — to provide an opportunity for a new rival to operate a significant gateway to search the internet, free of Google's monopoly control," Justice Department lawyers wrote in the filing... Judge Amit Mehta, of the U.S. District Court for the District of Columbia, who had ruled that Google held an illegal monopoly, will decide on the final remedies in April. The article quotes a Google spokesperson's response: that the Justice Department's "sweeping" proposals "continue to go miles beyond the court's decision, and would harm America's consumers, economy and national security."

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